3-Amino-2-naphthoic acid

CAS: 5959-52-4

Ref. 3D-FA00337

Produktinformation

• Name: 3-Amino-2-naphthoic acid
• Synonyme: 2-Amino-3-carboxynaphthalene, 2-Amino-3-naphthoic acid, 2-Aminonaphthalene-3-carboxylic acid, 2-Naphthalenecarboxylic acid, 3-amino-, 2-Naphthoic acid, 3-amino-, 3-Amino-2-naphthalenecarboxylic acid, 3-Aminoisonaphthoic acid, 3-Aminonaphthalene-2-Carboxylate, 3-Aminonaphthalene-2-Carboxylic Acid, Brn 0744099, Nsc 37061, β-Naphthylamine-3-carboxylic acid
• CAS: 5959-52-4

Beschreibung

3-Amino-2-naphthoic acid (3AN) is a metabolite of gabapentin that is excreted in the urine. It has been shown to be present in the urine of patients with chronic kidney disease, and is thought to be involved in the pathogenesis of this disease. 3AN has also been detected in carbon disulphide exposed rats, where it may contribute to renal damage. The biological properties of 3AN are not well understood, but it has been shown to have biochemical properties similar to those of gabapentin. 3AN is active against some bacteria and fungi, but not others. 3AN binds covalently to DNA, forming adducts that inhibit DNA synthesis and transcription. The fluorescence probe methyl anthranilate can be used as a fluorescent dye for detection of 3AN in biological samples.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 187.19 g/mol
• Formel: C₁₁H₉NO₂
• Reinheit: Min. 95%
• Farbe/Form: Yellow Powder
• InChl: InChI=1S/C11H9NO2/c12-10-6-8-4-2-1-3-7(8)5-9(10)11(13)14/h1-6H,12H2,(H,13,14)
• InChI Key: InChIKey=XFXOLBNQYFRSLQ-UHFFFAOYSA-N
• SMILES: Nc1cc2ccccc2cc1C(=O)O