Acetoacetate-m-xylidide

CAS: 97-36-9

Ref. 3D-FA05927

Produktinformation

• Name: Acetoacetate-m-xylidide
• Synonyme: 1-Acetoacetylamino-2,4-dimethylbenzene, 2',4'-Acetoacetoxylidide, 2',4'-Dimethylacetoacetanilide, 2,4-Acetoacetoxylidide, 2′,4′-Dimethylacetoacetanilide, Acetoacet-M-Xylidide, Acetoacetic acid m-xylidide, Acetoaceto-m-xylidide, Acetoacetyl-m-xylidide, Butanamide, N-(2,4-dimethylphenyl)-3-oxo-, N-(2,4-Dimethylphenyl)-3-Oxobutyramide, N-(2,4-Dimethylphenyl)acetoacetamide, N-(2,4-dimethylphenyl)-2-oxobutanamide, N-(2,4-dimethylphenyl)-3-oxobutanamide, N-Acetoacetyl-2,4-xylidine, NSC 8398, o,p-Dimethylacetoacetanilide

Beschreibung

Acetoacetate-m-xylidide (AAX) is a compound that is used as a reagent to detect protein adducts. It reacts with the amino groups of proteins to form an acetoacetate derivative, which can be detected by mass spectrometry or other analytical methods. The lability of AAX and its reactivity with oxygen make it a poor choice for use in the presence of air. The optimal pH for AAX is acidic, so it must be dissolved in water before use. AAX is used to detect proteins that have been modified by exposure to acid or alkaline environments. This chemical has also been shown to react with haemoglobin and s. aureus, but not p. aeruginosa or E. coli, due to their different structure of the protein cysteine residues. The maximum activation of AAX occurs at pH 4-7, and it becomes fully active at pH 3-4; this chemical does not

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 205.25 g/mol
• Formel: C₁₂H₁₅NO₂
• Reinheit: Min. 95 Area-%
• Farbe/Form: Powder
• InChl: InChI=1S/C12H15NO2/c1-8-4-5-11(9(2)6-8)13-12(15)7-10(3)14/h4-6H,7H2,1-3H3,(H,13,15)
• InChI Key: InChIKey=HGVIAKXYAZRSEG-UHFFFAOYSA-N
• SMILES: CC(=O)CC(=O)Nc1ccc(C)cc1C