N-Acetyl-L-isoleucyl-L-alpha-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine

CAS: 211990-57-7

Ref. 3D-FA103303

Produktinformation

• Name: N-Acetyl-L-isoleucyl-L-alpha-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine
• Synonyme: Caspase 8 Substrate 1F, Fluorogenic, Caspase-8 Fluorogenic Substrate, Granzyme B Substrate I, Colorimetric, Ac-Ietd-Afc, Ac-Ile-Glu-Thr-Asp-7-Amino-4-Trifluoro-Methylcoumarin, Ac-Ile-Glu-Thr-Asp-Afc, N-Acetyl-Ile-Glu-Thr-Asp-(7-Amino-4-Trifluoromethylcoumarin), N-Acetyl-Ile-Glu-Thr-Asp-7-Amino-4-Trifluoromethylcoumarin Afc
• CAS: 211990-57-7

Beschreibung

This drug has been shown to have an apoptotic effect on k562 cells, a minimal toxicity profile in monocytes and macrophages, and no effect on the growth factor. It also inhibits the mitochondrial membrane potential, which is critical for maintaining the balance between cell survival and death. This drug may be useful in treating prostate cancer cells by inhibiting the activation of intracellular targets such as fatty acid synthase or phospholipases A2. The drug has also been shown to inhibit ischemia-reperfusion injury in mouse lung tissue by targeting apical membrane proteins.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 729.66 g/mol
• Formel: C₃₁H₃₈F₃N₅O₁₂
• Reinheit: Min. 95%