KPT 9274

CAS: 1643913-93-2

Ref. 3D-FA103866

Produktinformation

• Name: KPT 9274
• Synonyme: (2E)-3-(6-Amino-3-pyridinyl)-N-[[5-[4-[(4,4-difluoro-1-piperidinyl)carbonyl]phenyl]-7-(4-fluorophenyl)-2-benzofuranyl]methyl]-2-prop enamide

Beschreibung

KPT 9274 is a molecule that binds to the citric acid cycle effector protein, β-catenin. It has minimal toxicity and is energy-independent. KPT 9274 blocks ATP production by binding to the death protein and inhibits atp production. KPT 9274 has been shown to be effective against high-risk disease such as acute myeloid leukemia (AML). The pharmacokinetic properties of KPT 9274 have been studied in vivo using a rat model. This drug is metabolized by fatty acid oxidation and glucuronidation in the liver and excreted in bile.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 610.63 g/mol
• Formel: C₃₅H₂₉F₃N₄O₃
• Reinheit: Min. 95%