H-DL-Ala-OEt·HCl

CAS: 17344-99-9

Ref. 3D-FA107888

Produktinformation

• Name: H-DL-Ala-OEt·HCl
• CAS: 17344-99-9

Beschreibung

H-DL-Ala-OEt·HCl (Dabigatran) is a quinolizidine alkaloid that is used in the treatment of patients with atrial fibrillation. It has been shown to inhibit the activity of the enzyme amine oxidase, which converts l-arginine to l-glutamic acid. Dabigatran etexilate, an ester prodrug of dabigatran, is hydrolyzed by esterases in blood plasma to release dabigatran, which then blocks the conversion of l-arginine to l-glutamic acid. This inhibition leads to a decrease in platelet aggregation and thrombin formation and thereby reduces blood clotting. Dabigatran etexilate also binds to primary amines on proteins such as albumin and α1-acid glycoprotein. This binding prevents the binding of other drugs such as warfarin or cl

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 153.61 g/mol
• Formel: C₅H₁₁NO₂·HCl
• Reinheit: Min. 95%