Apelin-13 (human, bovine, mouse, rat)

CAS: 217082-58-1

Ref. 3D-FA109297

Produktinformation

• Name: Apelin-13 (human, bovine, mouse, rat)
• Synonyme: H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH, 15: PN: WO2004081198 SEQID: 4 claimedsequence, 1: PN: WO2009033784 PAGE: 98 claimed protein, 2: PN:WO2009033819 PAGE: 103 claimed protein, 65-77-Apelin (Mus musculus), 65-77-Apelin, prepro-, Apelin-13, Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

Beschreibung

Apelin-13 is a peptide hormone that regulates the release of insulin and has been shown to play a role in metabolic disorders. It is a member of the apelin family, which includes human, bovine, and mouse apelin-12, as well as rat apelin-13. Apelin-13 binds to ATP-binding cassette transporter type 2 (ABC2) and increases autophagy by increasing its expression. Apelin-13 also induces mitochondrial membrane potential changes and neuronal death. These effects are mediated by an increase in reactive oxygen species production. Apelin-13 has been shown to be effective in treating experimental models of Parkinson's disease and Alzheimer's disease.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 1,550.83 g/mol
• Formel: C₆₉H₁₁₁N₂₃O₁₆S
• Reinheit: Min. 95%