Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide

CAS: 339990-02-2

Ref. 3D-FA109732

Produktinformation

• Name: Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide
• Synonyme: iA?5p, Beta-sheet Breaker Peptide ?iA 5pAc-Leu-Pro-Phe-Phe-Asp-NH2, 10:PN: WO03050139 SEQID: 15 claimed protein, 3: PN: WO0134631 PAGE: 35 claimedprotein, As 602704, Ac-Leu-Pro-Phe-Phe-Asp-Nh2
• CAS: 339990-02-2

Beschreibung

Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a peptide that was generated by incubating β-amyloid with the protease papain. This peptide has been shown to induce population and biochemical changes in cells, including focusing of β-amyloid aggregates. It also induces reactive oxygen species and promotes extracellular protofibril formation. Acetyl-(Pro18,Asp21)-Amyloid b-Protein (17-21) amide is a conjugate of acetylated lysine residues and amyloid β-protein that can be used as an anti-amyloid therapeutic. The peptide is characterized by dichroism spectroscopy, which has revealed its specific binding to the fibrils' surface.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 678.78 g/mol
• Formel: C₃₅H₄₆N₆O₈
• Reinheit: Min. 95%