
H-Asp-Asp-Asp-OH
CAS:
Ref. 3D-FA110342

Produktinformation
Name:H-Asp-Asp-Asp-OH
Marke:Biosynth
Beschreibung:H-Asp-Asp-Asp-OH is a peptide that has been shown to disrupt the cytosol and cause apoptosis. It can also induce proteolytic maturation and modulate autocatalytic functions. H-Asp-Asp-Asp-OH induces apoptosis by activating caspase 9 and caspase 3, which cleaves poly (ADP ribose) polymerase (PARP). This leads to DNA fragmentation, chromatin condensation, nuclear fragmentation, cell shrinkage, membrane blebbing, and nuclear pyknosis. H-Asp-Asp-Asp-OH binds to the regulatory domain of caspase 9 and prevents it from being activated. The peptide also activates caspase 8 by binding to its regulatory domain, which then activates caspases 3 and 7. H-Asp-Asp-Asp-OH also stimulates the release of granzyme B from cytot
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Chemische Eigenschaften
Molekulargewicht:363.28 g/mol
Formel:C12H17N3O10
Reinheit:Min. 95%