Z-Asp-Glu-Val-Asp-chloromethylketone

CAS: 250584-13-5

Ref. 3D-FA111069

Produktinformation

• Name: Z-Asp-Glu-Val-Asp-chloromethylketone
• Synonyme: Z-DEVD-CMK, Z-Asp-Glu-Val-Asp-Chloromethylketone, Z-Asp-Glu-Val-Asp-Cmk, Z-Devd-Cmk
• CAS: 250584-13-5

Beschreibung

Z-Asp-Glu-Val-Asp-chloromethylketone is a reactive compound that inhibits the activity of proteases and induces neuronal death. Z-Asp-Glu-Val-Asp-chloromethylketone has been shown to induce necrotic cell death in malignant brain cells and has neurotrophic properties. It also causes mitochondrial membrane depolarization, which leads to mitochondrial cytochrome c release and subsequent apoptosis. The reaction mechanism is still unclear but it may involve hydrogen bonding between the ketone group and the amide nitrogen atom of the aspartate residue.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 643.04 g/mol
• Formel: C₂₇H₃₅ClN₄O₁₂
• Reinheit: Min. 95%