Z-Asp-Glu-Val-Asp-chloromethylketone

CAS: 250584-13-5

Ref. 3D-FA111069

Produktinformation

• Name: Z-Asp-Glu-Val-Asp-chloromethylketone
• Synonyme: Z-DEVD-CMK
• Marke: Biosynth
• Beschreibung: Z-Asp-Glu-Val-Asp-chloromethylketone is a reactive compound that inhibits the activity of proteases and induces neuronal death. Z-Asp-Glu-Val-Asp-chloromethylketone has been shown to induce necrotic cell death in malignant brain cells and has neurotrophic properties. It also causes mitochondrial membrane depolarization, which leads to mitochondrial cytochrome c release and subsequent apoptosis. The reaction mechanism is still unclear but it may involve hydrogen bonding between the ketone group and the amide nitrogen atom of the aspartate residue.

Chemische Eigenschaften

• Molekulargewicht: 643.04 g/mol
• Formel: C₂₇H₃₅ClN₄O₁₂
• Reinheit: Min. 95%