(2E)-3-(3-Aminophenyl)acrylic acid

CAS: 127791-53-1

Ref. 3D-FA116562

Produktinformation

• Name: (2E)-3-(3-Aminophenyl)acrylic acid
• Synonyme: 2-Propenoic acid, 3-(3-aminophenyl)-, (2E)-

Beschreibung

(2E)-3-(3-Aminophenyl)acrylic acid is a diazonium salt that is used in the preparation of 3-nitrobenzaldehyde and other diazo compounds. It can be prepared by the reaction of nitrous acid with aniline, followed by hydrolysis and subsequent sulfonylation. The sequence of reactions is shown below:
It has been reported that (2E)-3-(3-aminophenyl)acrylic acid can be used to prepare cinnamic acids by condensation with methyl esters. It has also been found that belinostat, a DNA topoisomerase I inhibitor, can be synthesized from this compound.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 163.17 g/mol
• Formel: C₉H₉NO₂
• Reinheit: Min. 95%
• InChl: InChI=1S/C9H9NO2/c10-8-3-1-2-7(6-8)4-5-9(11)12/h1-6H,10H2,(H,11,12)/b5-4+
• InChI Key: InChIKey=JNXMJSYJCFTLJB-SNAWJCMRSA-N
• SMILES: Nc1cccc(/C=C/C(=O)O)c1