4-(1-Adamantyl)benzenesulfonyl chloride

CAS: 144174-50-5

Ref. 3D-FA117188

Produktinformation

• Name: 4-(1-Adamantyl)benzenesulfonyl chloride

Beschreibung

4-Adamantylbenzenesulfonyl chloride is a conformationally constrained analogue of the natural product 1,2-dihydrobenzofuran. It is a potent inhibitor of human cytochrome P450 enzymes, with Ki values in the range of 2 to 10 nM. 4-Adamantylbenzenesulfonyl chloride binds to the active site of cytochrome P450 and blocks access to substrate, thereby inhibiting the metabolism of drugs such as phenytoin and propranolol. 4-Adamantylbenzenesulfonyl chloride can be used as a probe for investigating enzyme activity in vitro or in vivo.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 310.84 g/mol
• Formel: C₁₆H₁₉ClO₂S
• Reinheit: Min. 95%
• Farbe/Form: Powder