AR-R 17779 hydrochloride

CAS: 178419-42-6

Ref. 3D-FA145501

Produktinformation

• Name: AR-R 17779 hydrochloride
• Synonyme: (3S)-Spiro[1-azabicyclo[2.2.2]octane-3,5'-oxazolidine]-2'-one hydrochloride
• Marke: Biosynth
• Beschreibung: AR-R 17779 is a selective agonist for α7 nicotinic acetylcholine receptors (nAChRs) (Ki value = 190 nM for rat α7 receptor). This compound has use as a tool to study the function of α7 nicotinic receptors. One such study revealed a role for α7 nicotinic receptors in nicotine-mediated excitatory effects on hippocampal learning and memory. AR-R17779 reduces formation of atherosclerotic plaques and abdominal aortic aneurysms in apolipoprotein E-deficient mice.

Chemische Eigenschaften

• Molekulargewicht: 218.68 g/mol
• Formel: C₉H₁₄N₂O₂•HCl
• Reinheit: Min. 95%
• Farbe/Form: White Powder