AOP

CAS: 156311-85-2

Ref. 3D-FA15661

Produktinformation

• Name: AOP
• Synonyme: 7-(Azabenzotriazol-1-yl)oxy tris(dimethylamino)phosphonium hexafluorophosphate
• Marke: Biosynth
• Beschreibung: AOP is a phosphonium salt and a HOAt derivative employed as a coupling reagent for peptide synthesis. AOP can be used in solution and solid-phase synthesis, is highly efficient with both linear and cyclic peptides, allows to achieve good yields, is a racemisation suppressant and has good reaction rates. AOP is soluble in DMF and requires presence of a base such as Hünig’s base. The drawback of using AOP is the formation of the toxic and carcinogenic by-product HMPA, therefore, it must be handled with care. The pyrrolidino derivative PyAOP is a good alternative to AOP as it achieves comparable performances, but generates a less toxic by-product.

Chemische Eigenschaften

• Molekulargewicht: 443.27 g/mol
• Formel: C₁₁H₂₁F₆N₇OP₂
• Reinheit: Min. 95%
• Farbe/Form: Powder