5alpha-Pregnan-3a-ol-20-one

CAS: 516-54-1

Ref. 3D-FA158661

Produktinformation

• Name: 5alpha-Pregnan-3a-ol-20-one
• Synonyme: 3α-Hydroxy-5α-pregnan-20-one3α-OH-DHPAllopregnan-3α-ol-20-oneAllopregnanolone, (+)-3α-Hydroxy-5α-pregnan-20-one, (3α)-Allopregnanolone, (3α,5α)-3-Hydroxypregnan-20-one, 3α,5α-Pregnanolone, 3α,5α-THP, 3α,5α-Tetrahydroprogesterone, 3α-Hydroxy-5α-dihydroprogesterone, 3α-Hydroxy-5α-pregnane-20-one, 5α-Pregnan-20-one, 3α-hydroxy-, 5α-Pregnan-3α-ol-20-one, 5α-Pregnane-3α-ol-20-one, Allopregnan-3α-ol-20-one, Allopregnanolone, Allopregnanolone (SAGE-547), Allotetrahydroprogesterone, Brexanolone, Pregnan-20-one, 3-hydroxy-, (3α,5α)-, Sage 547, Zulresso

Beschreibung

5alpha-Pregnan-3a-ol-20-one is a low potency endogenous steroid that has been shown to have physiological effects in the brain. It is synthesized from progesterone by 3β-hydroxysteroid dehydrogenase and 5α-reductase type I and metabolized through pregnane X receptor (PXR) and constitutive androstane receptor (CAR). 5alpha-Pregnan-3a-ol-20-one may be involved in the regulation of neuronal death and is found to have a protective effect on experimental models against glutamate induced neuronal death. 5alpha-Pregnan-3a-ol-20-one has also been found to be present at physiological levels in maternal blood, which may be associated with its role in fetal development.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 318.49 g/mol
• Formel: C₂₁H₃₄O₂
• Reinheit: Min. 98 Area-%
• Farbe/Form: White Off-White Powder