(S)-Acenocoumarol

CAS: 66556-78-3

Ref. 3D-FA16914

Produktinformation

• Name: (S)-Acenocoumarol
• Synonyme: (S)-4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-1-benzopyran-2-one(-)-3-(a-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin(-)-Acenocou marin, 4-Hydroxy-3-[(1S)-1-(4-nitrophenyl)-3-oxobutyl]-2H-1-benzopyran-2-one, 2H-1-Benzopyran-2-one, 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-, (S)-, (-)-Acenocoumarin, 2H-1-Benzopyran-2-one, 4-hydroxy-3-[(1S)-1-(4-nitrophenyl)-3-oxobutyl]-

Beschreibung

(S)-Acenocoumarol is a drug that is metabolized by cytochrome P450 2C19 to form the active metabolite (R)-acenocoumarol. This drug is used in the prevention of clotting and stroke in people with atrial fibrillation or those who have had a transient ischemic attack. The pharmacological effect of this drug is mediated through its ability to inhibit the conversion of vitamin K to its active form, which leads to decreased production of prothrombin. Oral administration of (S)-acenocoumarol has been shown to increase blood levels in human liver biopsies due to its high uptake into this organ. Pharmacodynamics experiments indicate that constant doses of (S)-acenocoumarol produce dose-dependent pharmacological effects on human liver tissue.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 353.33 g/mol
• Formel: C₁₉H₁₅NO₆
• Reinheit: Min. 95%