R-(+)-Aminoglutethimide L-tartrate salt

CAS: 57344-88-4

Ref. 3D-FA17756

Produktinformation

• Name: R-(+)-Aminoglutethimide L-tartrate salt
• Synonyme: R-(+)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione L-tartrate saltd-Aminoglutethimide L-tartrate

Beschreibung

R-(+)-Aminoglutethimide is a potent inhibitor of mitochondrial electron transport and the cleavage enzyme 4-phenylimidazole. It inhibits mitochondrial ATP production by binding to the inner mitochondrial membrane and preventing the passage of electrons from cytochrome c oxidase to oxygen. This drug has been shown to be effective in treating corticotroph adenoma, a benign tumor of the anterior pituitary gland, which is due to excessive secretion of ACTH by the gland. R-(+)-Aminoglutethimide can also be used for treatment of Cushing's syndrome due to its ability to inhibit cortisol synthesis in the adrenal cortex. This drug has been shown to act as a potent inhibitor of progesterone synthesis in bovine and human ovaries, leading to decreased levels of pregnenolone, which is an important precursor for other steroid hormones such as testosterone or estrogens.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 382.37 g/mol
• Formel: C₁₇H₂₂N₂O₈
• Reinheit: Min. 95%
• Farbe/Form: White To Off-White Solid
• InChl: InChI=1S/C13H16N2O2.C4H6O6/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9;5-1(3(7)8)2(6)4(9)10/h3-6H,2,7-8,14H2,1H3,(H,15,16,17);1-2,5-6H,(H,7,8)(H,9,10)
• InChI Key: InChIKey=DQUXPVVSVXIQNE-UHFFFAOYSA-N
• SMILES: CCC1(c2ccc(N)cc2)CCC(=O)NC1=O.O=C(O)C(O)C(O)C(=O)O