p-Anisylidenephthalide

CAS: 4767-61-7

Ref. 3D-FA17940

Produktinformation

• Name: p-Anisylidenephthalide
• Synonyme: 3-(4-Methoxybenzylidene)phthalide3-(4-Methoxybenzal)phthalide3-[(4-Methoxyphenyl)methylene]-1(3H)-isobenzofuranone, (3Z)-3-(4-methoxybenzylidene)-2-benzofuran-1(3H)-one, 1(3H)-Isobenzofuranone, 3-[(4-methoxyphenyl)methylene]-, 3-(4-Methoxybenzal)phthalide, 3-(4-Methoxybenzylidene)phthalide, 3-(4-methoxybenzylidene)-2-benzofuran-1(3H)-one, 3-[(4-Methoxyphenyl)methylene]-1(3H)-isobenzofuranone, NSC 61720, Phthalide, 3-(p-methoxybenzylidene)-, 3-((4-Methoxyphenyl)methylene)phthalide

Beschreibung

P-Anisylidenephthalide is a hydrophobic inhibitor that binds to the active site of vegfr-2. It has been shown to inhibit the activity of vegfr-2 and downregulate the expression of vascular endothelial growth factor receptor 2 (VEGFR-2). P-Anisylidenephthalide also inhibits the binding of sorafenib, which is a drug used to treat cancer, to its vegfr-2 target. The interaction between these two compounds may be due to hydrophobic interactions and docking.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 252.26 g/mol
• Formel: C₁₆H₁₂O₃
• Reinheit: Min. 95%
• InChl: InChI=1S/C16H12O3/c1-18-12-8-6-11(7-9-12)10-15-13-4-2-3-5-14(13)16(17)19-15/h2-10H,1H3/b15-10-
• InChI Key: InChIKey=XBPLURLJIACOAL-GDNBJRDFSA-N
• SMILES: COc1ccc(/C=C2\OC(=O)c3ccccc32)cc1