Ataciguat
CAS:
Ref. 3D-FA18005
Produktinformation
Name:Ataciguat
Synonyme:
- 5-Chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]benzamideHMR 1766
Marke:Biosynth
Beschreibung:Activator of soluble guanylyl cyclase (sGC) which stimulates cGMP production and is effective in cells under oxidative stress. Ataciguat stimulates the heme-free form of the sGC enzyme via the sGC N-terminus of β1-subunit. Ataciguat can promote vasorelaxation and hypotension by restoring or potentiating the nitric oxide (NO) signalling pathway.
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Chemische Eigenschaften
Molekulargewicht:576.5 g/mol
Formel:C21H19Cl2N3O6S3
Reinheit:Min. 95%
Farbe/Form:Powder
InChl:InChI=1S/C21H19Cl2N3O6S3/c22-14-1-6-18(25-34(28,29)20-8-7-19(23)33-20)17(13-14)21(27)24-15-2-4-16(5-3-15)35(30,31)26-9-11-32-12-10-26/h1-8,13,25H,9-12H2,(H,24,27)
InChI Key:InChIKey=PQHLRGARXNPFCF-UHFFFAOYSA-N
SMILES:O=C(Nc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1cc(Cl)ccc1NS(=O)(=O)c1ccc(Cl)s1