4-Amino-6-chloropyrimidine-5-carbonitrile

CAS: 60025-09-4

Ref. 3D-FA33037

Produktinformation

• Name: 4-Amino-6-chloropyrimidine-5-carbonitrile
• Synonyme: 5-Pyrimidinecarbonitrile, 4-Amino-6-Chloro-

Beschreibung

The 4-Amino-6-chloropyrimidine-5-carbonitrile (4ACPC) is a new chemical entity that has been shown to have cytostatic properties in vitro. The compound is a potent inhibitor of lipid kinase and phosphatase activities and inhibits the proliferation of chronic lymphocytic leukemia cells. It is also active against prostate carcinoma xenografts and molt-4 cells, which are T-cell leukemia cells. 4ACPC has been shown to inhibit tumor growth in vivo in models of prostate cancer and Molt-4 lymphocytic leukemia. The compound was orally administered as a single dose to mice bearing xenograft tumors, with no evidence of toxicity.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 154.56 g/mol
• Formel: C₅H₃ClN₄
• Reinheit: Min. 95%