Ansamitocin P-3

CAS: 66584-72-3

Ref. 3D-FA35435

Produktinformation

• Name: Ansamitocin P-3
• Synonyme: 2'-De(acetylmethylamino)-2'-methylmaytansine, 2′-De(acetylmethylamino)-2′-methylmaytansine, 4,24-Dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosane, maytansine deriv., Ansamitocin P 3, Maytansinol isobutyrate, Maytansine, 2′-de(acetylmethylamino)-2′-methyl-

Beschreibung

Ansamitocin P-3 is a mutant strain of Actinosynnema pretiosum that was originally isolated from the soil near a coal mine in China. The strain has been expressed as a piperidine molecule and maytansinol (a molecule found in the Chinese herb, mayten). The Ansamitocin P-3 molecule has shown anticancer activity against human cancer cells, with IC50 values of 0.2 and 0.5 μM for human breast cancer cells and lung cancer cells, respectively. It also has antiviral activity against HIV-1 with an EC50 value of 3.2 μM.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 635.14 g/mol
• Formel: C₃₂H₄₃ClN₂O₉
• Reinheit: Min. 95%
• Farbe/Form: Powder