Angiotensin

CAS: 1407-47-2

Ref. 3D-FA41793

Produktinformation

• Name: Angiotensin
• Synonyme: Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His
• Marke: Biosynth
• Beschreibung: Made up of 9 amino acids, this Angiotensin 1-9 product, is a renin-angiotensin system (RAS) peptide produced when the angiotensin-converting enzyme type 2 (ACE2) hydrolyses the carboxy terminal leucine from angiotensin I (1-10). There is evidence to suggest that Angiotensin 1-9 is an antagonist of classical RAS signalling. RAS is highly important within the cardiovascular system in that it regulates blood pressure and electrolyte balance. However it can also inflict cardiac and vascular damage due to instigating structural remodelling and inflammation. It is therefore important to gain further understanding of Angiotensin’s role in RAS and how it influences cardiovascular disease. Studies have shown that when Angiotensin 1-9 was given to patients 2 weeks after myocardial infarction it caused a decreased cardiomyocyte hypertrophy in vivo and in vitro.; This product is available as a trifluoroacetate (TFA) salt and can be used in scientific and therapeutic development research.

Chemische Eigenschaften

• Reinheit: Min. 95 Area-%
• Farbe/Form: Powder