(3S,4S)-4-Amino-3-hydroxy-5-phenylpentanoic acid

CAS: 72155-50-1

Ref. 3D-FA48184

Produktinformation

• Name: (3S,4S)-4-Amino-3-hydroxy-5-phenylpentanoic acid
• Synonyme: AHPPA-OH, (-)-Ahppa, (3S,4S)-Ahppa, (S,S)-4-Amino-3-hydroxy-5-phenylpentanoic acid

Beschreibung

(3S,4S)-4-Amino-3-hydroxy-5-phenylpentanoic acid is an analog of (2R,3R)-2-amino-3-(hydroxymethyl)butanoic acid. It has been shown to be a potent inhibitor of the enzyme dipeptidyl peptidase IV (DPPIV), which breaks down tripeptides and inhibits immune responses. This inhibition causes hypotension in rats and humans. (3S,4S)-4-Amino-3-hydroxy-5-phenylpentanoic acid also has an isostere group that can be used as a substrate analogue for the formation of tripeptides. The hydrogen bond with the hydroxyl group on C1' plays an important role in its potency as an inhibitor of DPPIV.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 209.24 g/mol
• Formel: C₁₁H₁₅NO₃
• Reinheit: Min. 95%