L-Arginine beta-naphthylamide hydrochloride

CAS: 18905-73-2

Ref. 3D-FA52400

Produktinformation

• Name: L-Arginine beta-naphthylamide hydrochloride
• Synonyme: Arginine-bNA·HCl, H-Arg-.beta.NA . HCl, L-Arginine Beta-Naphthylamide Hydrochloride, N5-(diaminomethylidene)-N-naphthalen-2-yl-L-ornithinamide hydrochloride, N~5~-(diaminomethylidene)-N-naphthalen-2-yl-L-ornithinamide, N~5~-(diaminomethylidene)-N-naphthalen-2-ylornithinamide hydrochloride, Pentanamide, 2-amino-5-[(aminoiminomethyl)amino]-N-2-naphthalenyl-, monohydrochloride, (S)-, Valeramide, 2-amino-5-guanidino-N-2-naphthyl-, monohydrochloride, <span class="text-smallcaps">L</span>-
• CAS: 18905-73-2

Beschreibung

L-Arginine beta-naphthylamide hydrochloride (L-Arg) is a chemical compound that inhibits bacterial growth by binding to the enzyme arginase. This inhibition prevents the conversion of L-arginine to urea and ornithine, which are essential for bacterial growth. L-Arg has been shown to have an inhibitory effect on a mutant strain of Pseudomonas aeruginosa, which was resistant to ertapenem. The IC50 value of L-Arg was found to be 2.5 mM, with an EC50 value of 10 μM at 37°C in human liver cells. It has a pKa of 9.0 and an optimum pH of 7.2, making it more acidic than most other compounds in this class.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 335.83 g/mol
• Formel: C₁₆H₂₁N₅O·HCl
• Reinheit: Min. 95%
• Farbe/Form: Powder