2-Amino-5-iodobenzoic acid methyl ester

CAS: 77317-55-6

Ref. 3D-FA55376

Produktinformation

• Name: 2-Amino-5-iodobenzoic acid methyl ester
• Synonyme: Methyl 2-amino-5-iodobenzoate 5-Iodoanthranilic acid methyl ester, 5-Iodoanthranilic acid methyl ester, Anthranilic acid, 5-iodo-, methyl ester, Benzoic acid, 2-amino-5-iodo-, methyl ester, Methyl 2-Amino-5-Iodobenzoate, Methyl 5-iodoanthranilate

Beschreibung

2-Amino-5-iodobenzoic acid methyl ester (2AIBA) is a molecule that can be used as an activatable probe for imaging cancer. It has a profile suitable for radionuclide therapy and is also senescent. 2AIBA binds to DNA and inhibits the synthesis of proteins, leading to cell death. 2AIBA has potent inhibitory activity against murine melanoma cells and synergistic effects when combined with acridone. The section of tumour cells was shown to be reduced by 42% in mice when treated with 2AIBA, acridone, and radiation compared to mice treated with radiation alone.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 277.06 g/mol
• Formel: C₈H₈INO₂
• Reinheit: Min. 95%
• Farbe/Form: Powder