4-Amino-3-chlorobenzonitrile

CAS: 21803-75-8

Ref. 3D-FA64101

Produktinformation

• Name: 4-Amino-3-chlorobenzonitrile
• Synonyme: 3-Chloro-4-aminobenzonitrile, 3-Chloro-4-Aminbenzonitrile

Beschreibung

4-Amino-3-chlorobenzonitrile is a ligand that binds to the heme of cytochrome P450 (CYP) enzymes. It has been shown to have a pharmacokinetic profile in rats and mice with lung diseases, which is similar to that of 4-amino-2-bromobenzonitrile. This ligand inhibits CYP enzymes by competing with endogenous substrates for binding sites on the heme, leading to an increase in the metabolism of drugs such as carbonyl drugs. 4-Amino-3-chlorobenzonitrile also has potent inhibitory effects on efflux pumps in cells and may be used to treat drug resistant bacteria.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 152.58 g/mol
• Formel: C₇H₅ClN₂
• Reinheit: Min. 95%
• Farbe/Form: Powder
• InChl: InChI=1S/H3N/h1H3
• InChI Key: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#Cc1ccc(N)c(Cl)c1