Alantolactone

CAS: 546-43-0

Ref. 3D-FA65639

Produktinformation

• Name: Alantolactone
• Synonyme: Helenine, (3aR,5S,8aR,9aR)-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one, (3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylen-3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(3H)-on, (3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(3H)-one, (3aR,5S,8aR,9aR)-5,8a-Diméthyl-3-méthylène-3a,5,6,7,8,8a,9,9a-octahydronaphto[2,3-b]furan-2(3H)-one, (3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(3H)-one, (3aS,5R,8aS,9aS)-5,8a-dimethyl-3-methylidene-3a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(3H)-one, 4α<span class="text-smallcaps">H</span>-Eudesma-5,11(13)-dien-12-oic acid, 8β-hydroxy-, γ-lactone, 8b-Hydroxy-4aH-eudesm-5-en-12-oic Acid g-Lactone, Alant camphor, Elecampane camphor, Eupatal, Helenin, Inula camphor, NSC 333843, NSC 93131, Naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, [3aR-(3aα,5β,8aβ,9aα)]-, [3aR-(3aa,5b,8ab,9aa)]-3a,5,6,7,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2(3H)-one, naphtho[2,3-b]furan-2(3H)-one, 3a,5,6,7,8,8a,9,9a-octahydro-5,8a-dimethyl-3-methylene-, (3aR,5S,8aR,9aR)-
• CAS: 546-43-0

Beschreibung

Alantolactone is a natural product that has been shown to induce apoptosis in rat urinary bladder cancer cells. It binds to the substrate binding site of the enzyme and inhibits d-malic acid synthesis. Alantolactone also induces apoptosis in neural cells and squamous cell carcinoma cells, which may be due to its ability to bind with bcl-2 protein and induce apoptosis. This compound has antimicrobial potential against gram-positive bacteria, such as Staphylococcus aureus and Bacillus subtilis, but it does not have any activity against gram-negative bacteria, such as Escherichia coli. Alantolactone also has antitumor immunity effects on rat urine samples, which may be due to its ability to increase T helper 1 (Th1) response and decrease T helper 2 (Th2) response.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 232.32 g/mol
• Formel: C₁₅H₂₀O₂
• Reinheit: Min. 95%
• Farbe/Form: Powder