Aristolactam

CAS: 13395-02-3

Ref. 3D-FA74143

Produktinformation

• Name: Aristolactam
• Synonyme: 8-Methoxybenzo[f]-1,3-benzodioxolo[6,5,4-cd]indol-5(6H)-one, 8-methoxy[1,3]benzodioxolo[6,5,4-cd]benzo[f]indol-5(6H)-one, Aristololactam, Aristololactam I, Benzo[f]-1,3-benzodioxolo[6,5,4-cd]indol-5(6H)-one, 8-methoxy-, NSC 87406, Aristolactam I

Beschreibung

Aristolactam is a natural product that has been found to have cytotoxic activity against urothelial carcinoma. It is an aristolactam-type compound, which has been shown to be produced by the genus Velutinam. The structure of aristolactam was elucidated by LC-MS/MS analysis of an extract from the whole genome sequencing of this genus. Aristolactam was also purified from an ethyl acetate extract of Velutinam. In vitro assays and preparative HPLC showed that aristolactum was able to inhibit inflammatory responses in mouse macrophages and human monocytes at concentrations as low as 1 μM.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 293.27 g/mol
• Formel: C₁₇H₁₁NO₄
• Reinheit: Min. 95%
• Farbe/Form: Yellow Solid
• InChl: InChI=1S/C17H11NO4/c1-20-12-4-2-3-8-9(12)5-11-14-10(17(19)18-11)6-13-16(15(8)14)22-7-21-13/h2-6H,7H2,1H3,(H,18,19)
• InChI Key: InChIKey=MXOKGWUJNGEKBH-UHFFFAOYSA-N
• SMILES: COc1cccc2c1cc1c3c(cc4c(c32)OCO4)C(=O)N1