Azithromycin Impurity O

CAS: 763924-54-5

Ref. 3D-FA76673

Produktinformation

• Name: Azithromycin Impurity O
• Synonyme: 2-Desethyl-2-propylazithromycin
• Marke: Biosynth
• Beschreibung: The impurity O is a minor component found in the chromatographic purification of azithromycin. Impurity O is an antibiotic that has been shown to have antibacterial and anti-inflammatory properties. The impurity was first identified in the Chinese Pharmacopoeia and later included in the 2008 edition of the European Pharmacopoeia. Impurity O is produced by reacting aniline with sodium nitrite, followed by hydrolysis with sulfuric acid. The reaction produces 2-nitro-4-aminobenzoic acid, which can then be reduced to 2-amino-4-nitrobenzoic acid or oxidized to 4-aminobenzoate. Impurity O is found at a concentration of less than 0.1% in azithromycin preparations, but its biological activity has not been studied extensively.

Chemische Eigenschaften

• Molekulargewicht: 763.01 g/mol
• Formel: C₃₉H₇₄N₂O₁₂
• Reinheit: Min. 96 Area-%
• Farbe/Form: White Off-White Powder