4-bromo-1-hydroxynaphthalene-2-carboxylic acid

CAS: 5813-37-6

Ref. 3D-FAA81337

Produktinformation

• Name: 4-bromo-1-hydroxynaphthalene-2-carboxylic acid
• Synonyme: 2-Naphthalenecarboxylic Acid, 4-Bromo-1-Hydroxy-, 4-Bromo-1-hydroxy-2-naphthoic acid

Beschreibung

4-Bromo-1-hydroxynaphthalene-2-carboxylic acid (4BHN) is a spectroscopic compound that has been used as a radioligand to study the binding of dopamine and dopamine D3 receptors. This compound binds to the d3 receptor with high affinity and specificity, but it does not interact with the d1 or d2 receptors. 4BHN has been shown to act as an agonist at the dopamine D3 receptor. It also acts as an antagonist at the piperidine site of the dopamine D2 receptor. The effects of 4BHN are reversible, which means that it can be displaced by unlabeled 4BHN or other compounds that bind to the same site on the receptor. This technique is useful for studying drug interactions and for determining whether drugs have a subtype selectivity profile.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 267.1 g/mol
• Formel: C₁₁H₇BrO₃
• Reinheit: Min. 95%