Bz-Ala-Ala-D-Trp-Phe-D-Pro-Pro-Nle-NH2

CAS: 141636-65-9

Ref. 3D-FB108779

Produktinformation

• Name: Bz-Ala-Ala-D-Trp-Phe-D-Pro-Pro-Nle-NH2
• Synonyme: GR 94800

Beschreibung

Bz-Ala-Ala-D-Trp-Phe-D-Pro-Pro-Nle (BAAPPDNP) is a cytosolic Ca2+ antagonist. It inhibits the release of neurotransmitters and neurally induced contractions in rat ileum. BAAPPDNP has been shown to inhibit colonic inflammation by suppressing the production of proinflammatory cytokines, such as IL-6 and TNFα. This compound also inhibits the production of prostaglandin E2 (PGE2) in an in vitro study. BAAPPDNP is a saponin that binds to phospholipids on the cell membrane and blocks calcium channels, which leads to a decrease in intracellular calcium levels. The maleate salt of BAAPPDNP can be used for the treatment of colitis and enteritis caused by various bacteria, such as Clostridium perfringens, Clostridium difficile, Salmone

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 904.06 g/mol
• Formel: C₄₉H₆₁N₉O₈
• Reinheit: Min. 95%