N-(1,3-Benzodioxol-5-ylmethyl)-2-chloroacetamide

CAS: 40023-03-8

Ref. 3D-FB114058

Produktinformation

• Name: N-(1,3-Benzodioxol-5-ylmethyl)-2-chloroacetamide
• Synonyme: Acetamide, N-(1,3-benzodioxol-5-ylmethyl)-2-chloro-, N-[(Benzodioxol-5-yl)methyl]-2-chloroacetamide

Beschreibung

N-(1,3-Benzodioxol-5-ylmethyl)-2-chloroacetamide (BCA) is a dithiocarbamate that has significant cytotoxic activity against human lung cancer cell lines. It inhibits the growth of cancer cells by binding to nucleophilic sites on DNA and preventing DNA synthesis. BCA also inhibits the production of reactive oxygen species in cells. This inhibition enhances cisplatin's cytotoxicity in glioma cells, which may be due to a synergistic effect between these two drugs.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 227.64 g/mol
• Formel: C₁₀H₁₀ClNO₃
• Reinheit: Min. 95%
• InChl: InChI=1S/C10H10ClNO3/c11-4-10(13)12-5-7-1-2-8-9(3-7)15-6-14-8/h1-3H,4-6H2,(H,12,13)
• InChI Key: InChIKey=PLXGAUGZSOPIIG-UHFFFAOYSA-N
• SMILES: O=C(CCl)NCc1ccc2c(c1)OCO2