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N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide
CAS: 850879-09-3
Ref. 3D-FB151469
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Produktinformation
Name:
N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide
Synonyme:
- Mp 470
- Amuvatinib
Beschreibung:
N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide is a potent inhibitor of the protein kinase of the BCR/ABL family. It has been shown to inhibit cell proliferation and induce cell death in human myeloma cells. This drug has also been shown to inhibit the activity of toll-like receptor 4 involved in immune function and control of cancer by suppressing the expression of genes related to inflammation. N-(1,3-Benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl piperazinecarbothioamide also inhibits the growth of bacteria that are resistant to antibiotics and prevents infection caused by viruses.
Hinweis:
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
447.51 g/mol
Formel:
C23H21N5O3S
Reinheit:
Min. 95%
InChl:
InChI=1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14H2,(H,24,32)
InChI Key:
InChIKey=FOFDIMHVKGYHRU-UHFFFAOYSA-N
SMILES:
S=C(NCc1ccc2c(c1)OCO2)N1CCN(c2ncnc3c2oc2ccccc23)CC1
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