PyBroP

CAS: 132705-51-2

Ref. 3D-FB15669

Produktinformation

• Name: PyBroP
• Synonyme: Bromotripyrrolidinophosphonium hexafluorophosphate
• Marke: Biosynth
• Beschreibung: PyBroP is a phosphonium salt used in peptide coupling chemistry, analogous to PyCloP. PyBroP shows high efficiency in the coupling of N-methylated amino acids and α,α-disubstituted amino acids, with excellent yields, no epimerisation and fast reaction rates. PyBroP is a stable solid which can be used in a one-pot procedure and is soluble in the solvents commonly used for peptide coupling chemistry. PyBroP is a derivative of the phosphonium coupling reagent BOP but contains a pyrrolidine moiety in place of the dimethylamine of BOP. The aim behind the design of PyBroP was to prevent the formation of the extremely toxic and carcinogenic by-product HMPA generated with BOP, but with comparable performances.

Chemische Eigenschaften

• Molekulargewicht: 466.18 g/mol
• Formel: C₁₂H₂₄BrF₆N₃P₂
• Reinheit: Min. 97 Area-%
• Farbe/Form: Powder