SGC GAK 1

CAS: 2226517-76-4

Ref. 3D-FB166265

Produktinformation

• Name: SGC GAK 1
• Synonyme: 6-Bromo-N-(3,4,5-trimethoxyphenyl)-4-quinolinamine
• Marke: Biosynth
• Beschreibung: A potent and selective inhibitor of cyclin G-associated kinase (GAK) with Ki of 3.1 nM. The compound has more than 50-fold selectivity over the closest off-target kinase RIPK2, making it a potent tool for the study of GAK biology. SGC-GAK-1 was tested in vitro in human prostate carcinoma cell lines and showed strong growth inhibition in cell lines with androgen-dependent growth.

Chemische Eigenschaften

• Molekulargewicht: 388.04226
• Formel: C₁₈H₁₇BrN₂O₃
• Reinheit: Min. 95%
• Farbe/Form: Solid
• InChl: InChI=1S/C18H17BrN2O3/c1-22-16-9-12(10-17(23-2)18(16)24-3)21-15-6-7-20-14-5-4-11(19)8-13(14)15/h4-10H,1-3H3,(H,20,21)
• InChI Key: InChIKey=AUOSKLDNVNGKRR-UHFFFAOYSA-N
• SMILES: COc1cc(Nc2ccnc3ccc(Br)cc23)cc(OC)c1OC