Bis(carboxymethyl)trithiocarbonate

CAS: 6326-83-6

Ref. 3D-FB166972

Produktinformation

• Name: Bis(carboxymethyl)trithiocarbonate
• Synonyme: 2,2'-(Carbonothioyldisulfanediyl)Diacetate, 2,2'-(Carbonothioyldisulfanediyl)Diacetic Acid, 2,2′-[Carbonothioylbis(thio)]bis[acetic acid], 2-(Carboxymethylsulfanylcarbothioylsulfanyl)acetic acid, 2-([[(Carboxymethyl)sulfanyl]methanethioyl]sulfanyl)acetic acid, 3,5-Dithia-4-Thioxo-1,7-Heptanedioic Acid, Acetic acid, 2,2′-[carbonothioylbis(thio)]bis-, Carbonic acid, trithio-, bis(carboxymethyl) ester, Carbonic acid, trithio-, diester with mercaptoacetic acid, Di(carboxymethyl) trithiocarbonate, NSC 30797, Thiocarbonyldithioglycolic acid, Trithiocarbodiglycolic acid

Beschreibung

Bis(carboxymethyl)trithiocarbonate (BCMT) is a potent inhibitor of Cox-2. BCMT has been shown to inhibit COX-2 activity in animals, and it was found to be safe for use in humans. BCMT also inhibits the activity of other enzymes involved in inflammation, such as lipoxygenase, 5-lipoxygenase, and cyclooxygenase. This molecule has been shown to have anti-cancer properties and is being used clinically to treat cancers with high levels of Cox-2 expression. BCMT inhibits the production of proinflammatory cytokines and chemokines that promote tumor growth by inhibiting the function of cell signaling pathways. The molecular structure of this compound contains a phosphate group, which may be responsible for its potent inhibitory activity on Cox-2 enzyme.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 226.3 g/mol
• Formel: C₅H₆O₄S₃
• Farbe/Form: Yellow Powder
• InChl: InChI=1S/C5H6O4S3/c6-3(7)1-11-5(10)12-2-4(8)9/h1-2H2,(H,6,7)(H,8,9)
• InChI Key: InChIKey=GQECANUIPBFPLA-UHFFFAOYSA-N
• SMILES: O=C(O)CSC(=S)SCC(=O)O