Produktinformation
Name:
(S)-Bendroflumethiazide
Kontrolliertes Produkt
Synonyme:
- (3S)-3,4-Dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Beschreibung:
(S)-Bendroflumethiazide is a diuretic that belongs to the class of thiazide-type diuretics. It is a racemic mixture of two enantiomers and has been shown to be effective in the treatment of hypertension and edema. The (S) form, which is the more potent form, has been shown to be more selective for potassium excretion than the (R) form. This drug has been shown to inhibit renal electrolyte transport by decreasing sodium reabsorption in the proximal tubule, leading to increased sodium excretion. The inhibition of sodium reabsorption can also lead to a decrease in potassium excretion.
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Marke:
Biosynth
Langzeitlagerung:
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Chemische Eigenschaften
Molekulargewicht:
421.42 g/mol
Formel:
C15H14F3N3O4S2
Reinheit:
Min. 95%
InChl:
InChI=1S/C15H14F3N3O4S2/c16-15(17,18)10-7-11-13(8-12(10)26(19,22)23)27(24,25)21-14(20-11)6-9-4-2-1-3-5-9/h1-5,7-8,14,20-21H,6H2,(H2,19,22,23)/t14-/m0/s1
InChI Key:
InChIKey=HDWIHXWEUNVBIY-AWEZNQCLSA-N
SMILES:
NS(=O)(=O)c1cc2c(cc1C(F)(F)F)N[C@H](Cc1ccccc1)NS2(=O)=O
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