6-Benzyloxygramine
CAS: 57765-22-7
Ref. 3D-FB18513
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Produktinformation
Name:
6-Benzyloxygramine
Synonyme:
- (6-Benzyloxyindolyl)-N,N-dimethylmethylamineN,N-dimethyl-6-(phenylmethoxy)-1H-indole-3-methanamineNSC 92545
Beschreibung:
6-Benzyloxygramine is a thyroxine (T4) metabolite that is formed by the oxidation of 6-hydroxylated T4. It has been shown to inhibit the conversion of T4 to triiodothyronine (T3). This conversion is catalyzed by type I 5'-deiodinase and requires NADPH as cofactor. 6-Benzyloxygramine can also be converted into skatole, which is a foul smelling compound that is excreted in the urine. The biosynthesis of 6-benzyloxygramine occurs in the liver and brain tissues, but it is not known how this compound is generated.
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
280.36 g/mol
Formel:
C18H20N2O
Reinheit:
Min. 95%
InChl:
InChI=1S/C18H20N2O/c1-20(2)12-15-11-19-18-10-16(8-9-17(15)18)21-13-14-6-4-3-5-7-14/h3-11,19H,12-13H2,1-2H3
InChI Key:
InChIKey=ARPLSLHBKDIBNO-UHFFFAOYSA-N
SMILES:
CN(C)Cc1c[nH]c2cc(OCc3ccccc3)ccc12
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