6-(Bromomethyl)-2-methyl-4(3H)-quinazolinone

CAS: 112888-43-4

Ref. 3D-FB19252

Produktinformation

• Name: 6-(Bromomethyl)-2-methyl-4(3H)-quinazolinone
• Synonyme: 6-(Bromomethyl)-2-methyl-4(1H)-quinazolinone, 6-(Bromomethyl)-2-Methyl-4(1H)-Quinazolinone, 4,6-(Bromomethyl)-2-Methy Quinazolinone, 6-Bromomethyl-3,4-dihydro-2-methylquinazoline-4-one, 6-(bromomethyl)-2-methylquinazolin-4(1H)-one, Levelling agent 102

Beschreibung

6-(Bromomethyl)-2-methyl-4(3H)-quinazolinone (6BMQ) is a synthetic molecule that has been designed to mimic the pharmacophores of quinazoline drugs. This compound is hydrolyzed by alkaline hydrolysis and acetylated in acidic conditions. 6BMQ binds to DNA and inhibits DNA synthesis, leading to cell death. It also has anti-cancer activity, which may be due to its ability to hybridize with DNA. 6BMQ is also a chalcone derivative with an acidic hydrolysis product.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 253.1 g/mol
• Formel: C₁₀H₉BrN₂O
• Reinheit: Min. 95%
• Farbe/Form: Off-White Powder
• InChl: InChI=1S/C10H9BrN2O/c1-6-12-9-3-2-7(5-11)4-8(9)10(14)13-6/h2-4H,5H2,1H3,(H,12,13,14)
• InChI Key: InChIKey=YAHALGNQKDVJLJ-UHFFFAOYSA-N
• SMILES: Cc1nc2ccc(CBr)cc2c(=O)[nH]1