Boc-3,4-dichloro-L-phenylalanine
CAS: 80741-39-5
Ref. 3D-FB47499
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Produktinformation
Name:
Boc-3,4-dichloro-L-phenylalanine
Synonyme:
- Boc-L-Phe(3,4-DiCl)-OHBoc-L-Phe(3,4-Cl2)-OH(S)-Boc-2-amino-3-(3,4-dichlorophenyl)propionic acid
- Boc-L-3,4-Dichlorophenylalanine
- Boc-3,4-Dichloro-L-phenylalanine
Beschreibung:
Boc-3,4-dichloro-L-phenylalanine (BOC-DPA) is an antagonist of the neurokinin NK2 receptor. It blocks the binding of tachykinins to the NK2 receptor, which prevents bronchoconstriction in humans and monkeys. BOC-DPA has been shown to have a high affinity for the human NK2 receptor and can be used as a pharmacological tool for studying this receptor. In vivo studies have shown that BOC-DPA does not induce bronchoconstriction in humans or monkeys. BOC-DPA is a synthetic molecule that has been shown to have pharmacokinetic properties similar to those of natural tachykinins, but with higher oral bioavailability and lower clearance rate.
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
334.19 g/mol
Formel:
C14H17Cl2NO4
Reinheit:
Min. 95%
InChl:
InChI=1S/C14H17Cl2NO4/c1-14(2,3)21-13(20)17-11(12(18)19)7-8-4-5-9(15)10(16)6-8/h4-6,11H,7H2,1-3H3,(H,17,20)(H,18,19)/t11-/m0/s1
InChI Key:
InChIKey=UGZIQCCPEDCGGN-NSHDSACASA-N
SMILES:
CC(C)(C)OC(=O)N[C@@H](Cc1ccc(Cl)c(Cl)c1)C(=O)O
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