N-alpha,epsilon-bis-Z-L-Lysine N-hydroxysuccinimide ester

CAS: 21160-83-8

Ref. 3D-FB47862

Produktinformation

• Name: N-alpha,epsilon-bis-Z-L-Lysine N-hydroxysuccinimide ester
• Synonyme: Z-L-Lys(Z)-OSu, (2,5-Dioxopyrrolidin-1-yl) (2S)-2,6-bis(phenylmethoxycarbonylamino)hexanoate, 2,5-dioxopyrrolidin-1-yl N~2~,N~6~-bis[(benzyloxy)carbonyl]lysinate, <span class="text-smallcaps">L</span>-Lysine, N²,N⁶-bis[(phenylmethoxy)carbonyl]-, 2,5-dioxo-1-pyrrolidinyl ester, Carbamic acid, [(1S)-1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-1,5-pentanediyl]bis-, bis(phenylmethyl) ester, Carbamic acid, [1-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]-1,5-pentanediyl]bis-, bis(phenylmethyl) ester, (S)-, N²,N⁶-Bis[(phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-lysine 2,5-dioxo-1-pyrrolidinyl ester, N^α,N^ε-Dibenzyloxycarbonyl-<span class="text-smallcaps">L</span>-lysine N-hydroxysuccinimide ester, NSC 250409, Succinimide, N-[(N²,N⁶-dicarboxy-<span class="text-smallcaps">L</span>-lysyl)oxy]-, dibenzyl ester, Z-Lys(Z)-OSu, na,N-epsilon-di-cbz-L-lysine N-*hydroxysuccinimid
• CAS: 21160-83-8

Beschreibung

N-alpha,epsilon-bis-Z-L-Lysine N-hydroxysuccinimide ester is a methyl ester of the amino acid Lysine. This drug has been shown to have antinociceptive effects in animal models and may be useful for the treatment of inflammatory pain. The active conformation of this drug is dependent on the presence of hydroxybenzimidazole (HOBt). In the absence of HOBt, the compound does not have any activity. Acetylation or amidation may also affect its activity. The reaction with nitric acid yields a nitro derivative, which can be reduced back to the original compound by catalytic hydrogenation using palladium on carbon. A carboxylic acid group at the amino terminus can be converted to an amide or amido group by treatment with an appropriate reagent such as acetonitrile. This drug binds to a catalytic site on

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 511.52 g/mol
• Formel: C₂₆H₂₉N₃O₈
• Reinheit: Min. 95%
• Farbe/Form: White Off-White Powder