5-Bromo-1H-indazole
CAS: 53857-57-1
Ref. 3D-FB50830
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| 2g | Ausgelaufen | ||
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Produktinformation
Name:
5-Bromo-1H-indazole
Synonyme:
- 5-Bromoindazole
- 5-Bromoindazol
Beschreibung:
5-Bromo-1H-indazole is an indazole derivative that has been shown to have potential use in the treatment of pain. It binds to the allosteric site on the enzyme gyrase, which is a DNA topoisomerase that controls the supercoiling of DNA. This binding prevents ATP from binding and inhibits DNA unwinding, leading to a decrease in DNA synthesis and cell division. 5-Bromo-1H-indazole also binds with high affinity at the allosteric site on the enzyme adenylate cyclase, which is involved in signal transduction pathways. Binding of 5-bromo-1H-indazole causes an increase in cAMP levels and leads to functional effects such as antinociception.
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Marke:
Biosynth
Langzeitlagerung:
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Chemische Eigenschaften
Molekulargewicht:
197.03 g/mol
Formel:
C7H5BrN2
Reinheit:
Min. 95%
InChl:
InChI=1S/C7H5BrN2/c8-6-1-2-7-5(3-6)4-9-10-7/h1-4H,(H,9,10)
InChI Key:
InChIKey=STVHMYNPQCLUNJ-UHFFFAOYSA-N
SMILES:
Brc1ccc2[nH]ncc2c1
MDL:
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