N-(tert-Butoxycarbonyl)-2-nitrobenzenesulfonamide

CAS: 198572-71-3

Ref. 3D-FB59870

Produktinformation

• Name: N-(tert-Butoxycarbonyl)-2-nitrobenzenesulfonamide
• Synonyme: N-Boc-2-nitrobenzenesulfonamide, N-Boc-O-Nitrobenzenesulfonamide, N-Boc-2-Nitrobenzenesulfonamide, Tert-Butyl [(2-Nitrophenyl)Sulfonyl]Carbamate
• CAS: 198572-71-3

Beschreibung

N-(tert-Butoxycarbonyl)-2-nitrobenzenesulfonamide is a macrocyclization agent that initiates and controls cyclization by alkylation of amines. The intramolecular nitroarene macrocyclization is stereoselectively controlled through diastereoselective synthesis. Nitrogen atoms in the nitroarene are activated with tert-butoxycarbonyl chloride to form an intermediate, which is then reacted with amines to form the macrocycle. This process is stereochemically mediated and produces a single diastereomer of the product.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 302.3 g/mol
• Formel: C₁₁H₁₄N₂O₆S
• Reinheit: Min. 95%