4-Bromo-2-fluoro-N-methylbenzamide

CAS: 749927-69-3

Ref. 3D-FB81945

Produktinformation

• Name: 4-Bromo-2-fluoro-N-methylbenzamide
• Synonyme: 4-Bromo-2-fluoro-N-methyl-benzamide, N-methyl-4-bromo-2-fluorobenzamide

Beschreibung

4-Bromo-2-fluoro-N-methylbenzamide is an impurity in the pharmaceutical drug nilutamide. It is a ligand that binds to the androgen receptor and inhibits the binding of dihydrotestosterone, reducing its effect on prostate cells. 4-Bromo-2-fluoro-N-methylbenzamide has been shown to have pharmacokinetic properties similar to nilutamide, which is a drug used for treating prostate cancer. This impurity is also found in small quantities in other drugs including cyclobutanone, 2-aminoisobutyric acid, and chloral hydrate. The elucidation of these impurities can help regulate the quality of pharmaceutical drugs.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 232.05 g/mol
• Formel: C₈H₇BrFNO
• Reinheit: Min. 95%
• Farbe/Form: White Off-White Powder
• InChl: InChI=1S/C8H7BrFNO/c1-11-8(12)6-3-2-5(9)4-7(6)10/h2-4H,1H3,(H,11,12)
• InChI Key: InChIKey=BAJCFNRLEJHPTQ-UHFFFAOYSA-N
• SMILES: CNC(=O)c1ccc(Br)cc1F