3'-O-Benzyl-2'-Deoxy-5-Trifluoromethyluridine

CAS: 96141-37-6

Ref. 3D-FB89144

Produktinformation

• Name: 3'-O-Benzyl-2'-Deoxy-5-Trifluoromethyluridine
• Synonyme: Ftc-092, 3'-O-Benzyl-2'-deoxy-5-(trifluoromethyl)uridine, alpha,alpha,alpha-Trifluoro-3'-O-(phenylmethyl)thymidine

Beschreibung

3'-O-Benzyl-2'-Deoxy-5-Trifluoromethyluridine (BDBMU) is a pyrimidine derivative that can be used as an antiviral drug. It inhibits the synthesis of DNA and RNA by inhibiting viral polymerase. BDBMU is a prodrug of uracil, which is converted to the active compound in tissues. The benzoylation reaction produces a fluorine atom at C5, which increases its potency. This drug has been shown to have minimal toxicity in tumor cells and has been used for the treatment of leukemia and other cancers.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 386.32 g/mol
• Formel: C₁₇H₁₇F₃N₂O₅
• Reinheit: Min. 95%
• InChl: InChI=1S/C17H17F3N2O5/c18-17(19,20)11-7-22(16(25)21-15(11)24)14-6-12(13(8-23)27-14)26-9-10-4-2-1-3-5-10/h1-5,7,12-14,23H,6,8-9H2,(H,21,24,25)/t12-,13+,14+/m0/s1
• InChI Key: InChIKey=REIREIWZLGFJBI-BFHYXJOUSA-N
• SMILES: O=c1[nH]c(=O)n([C@H]2C[C@H](OCc3ccccc3)[C@@H](CO)O2)cc1C(F)(F)F