Comin's reagent

CAS: 145100-51-2

Ref. 3D-FC10786

Produktinformation

• Name: Comin's reagent
• Synonyme: N-(5-Chloro-2-pyridyl)bis(trifluoromethanesulfonimide), 1-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, 2-[N,N-Bis(Trifluoromethanesulfonyl)Amino]-5-Chloropyridine, 2-[N,N-Bis(Trifluoromethylsulphonyl)amino]-5-chloropyridine, 2-[N,N-Bis(trifluoromethanesulphonyl)amino]-5-chloropyridine, 2-[N,N-Bis(trifluoromethylsulfonyl)amino]-5-chloropyridine, Bistrifluoromethylsulfonylaminochloropyridine, Comins, Comins' reagent, Methanesulfonamide, N-(5-chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridinamine, N,N-Bis(trifluoromethylsulfonyl)-5-chloro-2-pyridylamine, N-(5-Chloro-2-pyridinyl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide, N-(5-Chloro-2-pyridyl)-N-(trifluoromethanesulfonyl)trifluoromethanesulfonamide, N-(5-Chloro-2-pyridyl)triflimide, N-(5-chloropyridin-2-yl)-1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]methanesulfonamide, NSC 683533

Beschreibung

Comin's reagent is a sulfonation agent that reacts with an enolate and forms a sulfonic acid. The reaction can be used to synthesize chiral compounds. Comin's reagent is selective for the (R) configuration of acetylcholine and can be used to synthesize α-amino acids from chiral alcohols and esters. Comin's reagent is also used in the synthesis of neurotrophic or growth factor compounds, which are proteins that promote cell growth or differentiation. These functional groups are found in natural products such as nicotinic acetylcholine, thallusin, and growth factor.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 392.68 g/mol
• Formel: C₇H₃ClF₆N₂O₄S₂
• Reinheit: Min. 95%
• Farbe/Form: White Powder
• InChl: InChI=1S/C7H3ClF6N2O4S2/c8-4-1-2-5(15-3-4)16(21(17,18)6(9,10)11)22(19,20)7(12,13)14/h1-3H
• InChI Key: InChIKey=TUFGVZMNGTYAQD-UHFFFAOYSA-N
• SMILES: O=S(=O)(N(c1ccc(Cl)cn1)S(=O)(=O)C(F)(F)F)C(F)(F)F