µ-Conotoxin GIIIB

CAS: 140678-12-2

Ref. 3D-FC110369

Produktinformation

• Name: µ-Conotoxin GIIIB
• Synonyme: H-Arg-Asp-Cys-Cys-Thr-Hyp-Hyp-Arg-Lys-Cys-Lys-Asp-Arg-Arg-Cys-Lys-Hyp-Met-Lys-Cys-Cys-Ala-NH2 H-RDCCT(hyP)(hyP)RKCKDRRCK(hyP)MKCCA- NH2, Conotoxin GIIIB, H-Arg-Asp-Cys-Cys-Thr-Hyp-Hyp-Arg-Lys-Cys-Lys-Asp-Arg-Arg-Cys-Lys-Hyp-Met-Lys-Cys-Cys-Ala-NH2 (Disulfide bonds between Cys3 and Cys15/Cys4 and Cys20/ Cys10 and Cys21), Mu-Conotoxin Giiib

Beschreibung

The µ-conotoxin GIIIB is a potent nicotinic acetylcholine receptor antagonist and has been shown to inhibit the g1 phase of the cell cycle. It inhibits the binding of veratridine, a neurotoxin, to its receptor on the cell membrane. The µ-conotoxin GIIIB has also been shown to have an inhibitory effect on acetylcholine release from synaptosomes incubated with glucose and insulin. A magnetic resonance spectroscopy (MRS) study showed that µ-conotoxin GIIIB was able to bind to noradrenaline and dopamine receptors in rat erythrocytes. The µ-conotoxin GIIIB is a disulfide bond peptide that can be synthesized by solid-phase synthesis and purified by lc-ms/ms methods. Disulfide bonds are formed between Cys3 and Cys15, Cys4 and Cys20, Cys10

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 2,640.18 g/mol
• Formel: C₁₀₁H₁₇₅N₃₉O₃₀S₇
• Reinheit: Min. 95%