6-Chloropyridazine-3-thiol

CAS: 3916-78-7

Ref. 3D-FC121917

Produktinformation

• Name: 6-Chloropyridazine-3-thiol
• Synonyme: 6-Chloro-3-pyridazinethiol
• Marke: Biosynth
• Beschreibung: 6-Chloropyridazine-3-thiol is a potent inhibitor of platelet aggregation. This drug binds to the active site of the enzyme ADP-thrombin, thereby blocking the conversion of ADP to thrombin. 6-Chloropyridazine-3-thiol has been shown to have a high affinity for human liver microsomes, and is metabolized by conjugation with glutathione or glucuronide. 6CpT also inhibits the activation of factor V and factor VIII, which are involved in blood clotting. It is hypothesized that this inhibition may be due to its ability to bind to reactive chlorine atoms found on these proteins. 6-Chloropyridazine-3-thiol is a potent inhibitor of platelet aggregation, but it does not show any antiplatelet activity when used at low doses.

Chemische Eigenschaften

• Molekulargewicht: 146.6 g/mol
• Formel: C₄H₃ClN₂S
• Reinheit: Min. 95%
• Farbe/Form: White Powder
• InChl: InChI=1S/C4H3ClN2S/c5-3-1-2-4(8)7-6-3/h1-2H,(H,7,8)
• InChI Key: InChIKey=ABQHEWLZYZQXHY-UHFFFAOYSA-N
• SMILES: S=c1ccc(Cl)n[nH]1