2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one

CAS: 1013916-37-4

Ref. 3D-FC138696

Produktinformation

• Name: 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one
• Synonyme: 2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7-one, Pyrido[2,3-d]pyrimidin-7(8H)-one, 2-chloro-8-cyclopentyl-5-methyl-

Beschreibung

2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one is an industrial chemical that has been used as a potent inhibitor of cyclin dependent kinases. It is one of the first compounds to be identified with this property. 2CPMPY has shown activity against both cyclin D and CDK4, which are essential for mitosis. The compound is synthesized by the intramolecular cyclization of crotonic acid with 2-(chloromethyl)oxirane. This can be done in two ways: by thermal or photochemical means.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 263.72 g/mol
• Formel: C₁₃H₁₄ClN₃O
• Reinheit: Min. 95%
• InChl: InChI=1S/C13H14ClN3O/c1-8-6-11(18)17(9-4-2-3-5-9)12-10(8)7-15-13(14)16-12/h6-7,9H,2-5H2,1H3
• InChI Key: InChIKey=BSKNQSYIDZUXQT-UHFFFAOYSA-N
• SMILES: Cc1cc(=O)n(C2CCCC2)c2nc(Cl)ncc12