9-Chloroacridine
CAS: 1207-69-8
Ref. 3D-FC151363
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Produktinformation
Name:
9-Chloroacridine
Synonyme:
- Acridine, 9-chloro-
- Ai3-52323
- Nsc 51950
Beschreibung:
9-Chloroacridine is an acridone that has potent anti-inflammatory activity. It binds to the endothelin-A receptor, which is a G protein-coupled receptor. 9-Chloroacridine also inhibits neutrophil migration and the production of reactive oxygen species. It was shown to have significant cytotoxicity in cell culture and to react with hydrochloric acid to form two chemical species: amines and protonated molecules. Molecular docking analysis has been used to show that 9-chloroacridine interacts with the enzyme dihydropteridine reductase, which is involved in pteridine synthesis. The molecule was also shown to inhibit the growth of human cancer cells in vitro. This drug may be useful as a chemotherapy agent for treatment of cancer.
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Marke:
Biosynth
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Chemische Eigenschaften
Molekulargewicht:
213.66 g/mol
Formel:
C13H8ClN
Reinheit:
Min. 95%
InChl:
InChI=1S/C13H8ClN/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H
InChI Key:
InChIKey=BPXINCHFOLVVSG-UHFFFAOYSA-N
SMILES:
Clc1c2ccccc2nc2ccccc12
MDL:
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